CAS 35180-01-9: Essential Knowledge for Pharma Professionals

Table of Contents

• 1. Introduction to CAS 35180-01-9


• 2. Chemical Structure and Properties of CAS 35180-01-9


• 3. Applications of CAS 35180-01-9 in the Pharmaceutical Industry


• 4. Manufacturing Process of CAS 35180-01-9


• 5. Regulatory Considerations for CAS 35180-01-9


• 6. Safety and Handling of CAS 35180-01-9


• 7. Market Trends and Future Outlook for CAS 35180-01-9


• 8. Frequently Asked Questions


• 9. Conclusion

1. Introduction to CAS 35180-01-9

CAS 35180-01-9 is a key pharmaceutical intermediate widely recognized in the **medicinal chemistry** sector. Understanding its role is pivotal for professionals involved in drug development and production. This article aims to provide an all-encompassing overview of CAS 35180-01-9, exploring its significance, chemical properties, applications, and future prospects within the pharmaceutical industry.

2. Chemical Structure and Properties of CAS 35180-01-9

CAS 35180-01-9, known chemically as **N-(3-chlorophenyl)-2-methyl-2-(4-(trifluoromethyl)phenyl)acetamide**, has a complex molecular structure that contributes to its functionality.

2.1 Molecular Formula and Weight

The molecular formula of CAS 35180-01-9 is **C16H14ClF3N**, with a molecular weight of approximately **325.74 g/mol**. The presence of a trifluoromethyl group enhances its lipophilicity, making it an attractive candidate for various pharmaceutical applications.

2.2 Physical Properties

CAS 35180-01-9 exhibits specific physical properties that are crucial for its behavior in chemical reactions. It is typically a **white to off-white solid** with a melting point around **85-90°C**. Its solubility profile indicates moderate solubility in organic solvents, which is advantageous for formulation in various drug delivery systems.

3. Applications of CAS 35180-01-9 in the Pharmaceutical Industry

The applications of CAS 35180-01-9 are diverse, impacting several therapeutic areas. This compound serves as an essential intermediate in the synthesis of various pharmaceuticals, contributing to drug discovery and development.

3.1 Role in Drug Development

CAS 35180-01-9 is essential in synthesizing active pharmaceutical ingredients (APIs) that target **central nervous system disorders**, **pain management**, and **anti-inflammatory drugs**. Its structural properties allow for modifications that can enhance the efficacy and reduce side effects of the resultant drugs.

3.2 Synthesis of Target Compounds

Utilizing CAS 35180-01-9, chemists can create various **heterocyclic compounds** that play a critical role in developing new medications. This versatility makes it a vital component in medicinal chemistry research.

4. Manufacturing Process of CAS 35180-01-9

The manufacturing process of CAS 35180-01-9 involves several critical steps that ensure the compound's purity and efficacy.

4.1 Synthesis Routes

CAS 35180-01-9 can be synthesized through various chemical pathways, including **nucleophilic substitution** and **amide coupling reactions**. Each method requires precise control over reaction conditions to achieve optimal yields.

4.2 Quality Control Measures

Quality control is paramount in the production of CAS 35180-01-9. Sophisticated analytical techniques, such as **HPLC** and **NMR spectroscopy**, are employed to verify purity and identity, ensuring compliance with pharmaceutical standards.

5. Regulatory Considerations for CAS 35180-01-9

Pharmaceutical intermediates like CAS 35180-01-9 must adhere to strict regulatory guidelines to ensure safety and efficacy.

5.1 Compliance with International Standards

Manufacturers must comply with regulations set forth by organizations such as the **FDA** and **EMA**. This includes thorough documentation of the synthesis process, quality control measures, and safety assessments.

5.2 Environmental Regulations

The production and handling of CAS 35180-01-9 also require adherence to environmental regulations to mitigate the risk of harmful emissions and waste. Manufacturers must implement sustainable practices to reduce their ecological footprint.

6. Safety and Handling of CAS 35180-01-9

Ensuring the safety and proper handling of CAS 35180-01-9 is critical for pharmaceutical professionals.

6.1 Hazard Identification

CAS 35180-01-9 is classified as a **hazardous substance**. It may cause skin and eye irritation upon contact, and inhalation of its dust can lead to respiratory issues. Proper safety data sheets (SDS) should be provided.

6.2 Recommended Safety Precautions

Pharma professionals handling CAS 35180-01-9 should use appropriate personal protective equipment (PPE), including gloves, goggles, and respiratory protection. Furthermore, working in a well-ventilated area or a fume hood is advisable.

7. Market Trends and Future Outlook for CAS 35180-01-9

The market for CAS 35180-01-9 is influenced by ongoing trends in the pharmaceutical industry, including the rise of personalized medicine and an increasing focus on rare diseases.

7.1 Growing Demand for Pharmaceutical Intermediates

As the pharmaceutical industry evolves, the demand for high-quality intermediates like CAS 35180-01-9 is expected to grow. This increase is driven by the need for innovative therapies and the expansion of biopharmaceuticals.

7.2 Forecasting Future Developments

The future of CAS 35180-01-9 looks promising, with ongoing research into its applications in novel drug formulations. The industry's shift towards sustainability may also lead to the development of greener synthesis methods for CAS 35180-01-9.

8. Frequently Asked Questions

8.1 What is CAS 35180-01-9 used for?

CAS 35180-01-9 is primarily used as a pharmaceutical intermediate in the synthesis of various drugs targeting a range of medical conditions.

8.2 How is CAS 35180-01-9 synthesized?

CAS 35180-01-9 can be synthesized through nucleophilic substitution and amide coupling reactions, among other methods.

8.3 What safety precautions should be taken when handling CAS 35180-01-9?

When handling CAS 35180-01-9, it is essential to wear appropriate PPE, work in a ventilated area, and follow safety data sheet guidelines.

8.4 Are there any regulatory requirements for CAS 35180-01-9?

Yes, CAS 35180-01-9 must comply with regulations set by organizations like the FDA and EMA, focusing on safety, efficacy, and environmental impact.

8.5 What is the market outlook for CAS 35180-01-9?

The market for CAS 35180-01-9 is expected to grow due to the increasing demand for pharmaceutical intermediates and innovative therapies.

9. Conclusion

In summary, CAS 35180-01-9 plays a pivotal role in the pharmaceutical industry, serving as an essential intermediate in drug development. Understanding its chemical properties, applications, and regulatory considerations is vital for pharma professionals striving to excel in their fields. As the demand for innovative therapies continues to rise, so too does the significance of CAS 35180-01-9. Staying informed about its implications and future trends will ensure that industry professionals remain at the forefront of pharmaceutical advancements.